Trichloroethylene

Trichloroethylene
	Sample of trichloroethylene
Names
Pronunciation	/trʌɪˌklɔːrəʊˈɛθɪliːn/
	Preferred IUPAC name Trichloroethene
	Other names 1-Chloro-2,2-dichloroethylene; 1,1-Dichloro-2-chloroethylene; Acetylene Trichloride; Ethinyl Trichloride; Ethylene Trichloride; Terchlorethylene; Chloréthérise (archaic); Trade names: Algylen; Anamenth; Chlorylene; Gemalgene; Trethylene; Triclene; Trico; Triklone; Trilene; Trimar
Identifiers
CAS Number	79-01-6 ;
3D model (JSmol)	Interactive image; Interactive image; Interactive image;
Abbreviations	TCE, HCO-1120, Tri, Trichlor
ChEBI	CHEBI:16602 ;
ChEMBL	ChEMBL279816 ;
ChemSpider	13837280 ;
ECHA InfoCard	100.001.062
EC Number	201-167-4;
KEGG	C06790 ;
PubChem CID	6575;
RTECS number	KX4550000;
UNII	290YE8AR51 ;
UN number	1710
CompTox Dashboard (EPA)	DTXSID0021383 ;
	InChI InChI=1S/C2HCl3/c3-1-2(4)5/h1H Key: XSTXAVWGXDQKEL-UHFFFAOYSA-N ; InChI=1/C2HCl3/c3-1-2(4)5/h1H;
	SMILES Cl\C=C(/Cl)Cl; Cl\C=C(/Cl)Cl; ClC=C(Cl)Cl;
Properties
Chemical formula	C2HCl3
Molar mass	131.38 g·mol−1
Appearance	Colorless liquid
Odor	sweet, pleasant, chloroform-like
Density	1.46 g/cm3 at 20 °C
Melting point	−84.8 °C (−120.6 °F; 188.3 K) some sources also list –73 °C as the freezing point
Boiling point	86.7 °C (188.1 °F; 359.8 K)
Solubility in water	1.280 g/L
Solubility	Ether, ethanol, chloroform
log P	2.26
Vapor pressure	58 mmHg (0.076 atm) at 20 °C
Magnetic susceptibility (χ)	−65.8·10−6 cm3/mol
Refractive index (nD)	1.4777 at 19.8 °C
Viscosity	0.532 mPa·s
Pharmacology
ATC code	N01AB05 (WHO)
Hazards
	Occupational safety and health (OHS/OSH):
Main hazards	Acute exposure can cause dizziness and loss of consciousness, chronic exposure may increase cancer risk. Unstable in presence of sunlight and caustic soda.
	GHS labelling:
Pictograms
NFPA 704 (fire diamond)	2 1 0
Autoignition; temperature	420 °C (788 °F; 693 K)
Explosive limits	8–10.5%
	Lethal dose or concentration (LD, LC):
LD50 (median dose)	7000 mg/kg (oral, human); 4920 mg/kg (oral, rat), 29000 mg/kg (dermal, rabbit)
LC50 (median concentration)	8450 ppm (mouse, 4 hr); 26300 ppm (rat, 1 hr)
LCLo (lowest published)	2900 ppm (human); 37,200 ppm (guinea pig, 40 min); 5952 ppm (cat, 2 hr); 8000 ppm (rat, 4 hr); 11,000 ppm (rabbit)
	NIOSH (US health exposure limits):
PEL (Permissible)	TWA 100 ppm C 200 ppm 300 ppm (5-minute maximum peak in any 2 hours)
REL (Recommended)	Ca
IDLH (Immediate danger)	Ca [1000 ppm]
Safety data sheet (SDS)	Carl Roth
Legal status	BR: Class B1 (Psychoactive drugs); US: banned for medical use (1977), all use banned (2024);
Related compounds
Related vinyl halides	Vinyl chloride; Tetrachloroethylene; Trifluoroethylene
Related compounds	Chloroform; 1,1,1-Trichloroethane; 1,1,2-Trichloroethane; Chloral
Supplementary data page
	Trichloroethylene (data page)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Trichloroethylene (TCE, IUPAC name: trichloroethene) is an organochloride with the formula C₂HCl₃, commonly used as an industrial degreaser. It is a clear, colourless, non-flammable, volatile liquid with a sweet chloroform-like pleasant mild smell^[3] and burning sweet taste.^[11] Trichloroethylene has been sold under a variety of trade names. Under the trade names Trimar and Trilene, it was used as a volatile anesthetic and as an inhaled obstetrical analgesic. Industrial abbreviations include trichlor, Trike, Tricky and tri. It should not be confused with the similar 1,1,1-trichloroethane, which was commonly known as chlorothene.

^ ^a ^b "Trichloroethylene". Sigmaaldrich.com. Retrieved 20 October 2014.
^ "Trichloroethylene". www.chemsrc.com.
^ ^a ^b ^c ^d ^e ^f NIOSH Pocket Guide to Chemical Hazards. "#0629". National Institute for Occupational Safety and Health (NIOSH).
^ Venkatesulu, D.; Venkatesu, P.; Rao, M. V. Prabhakara (1997). "Viscosities and Densities of Trichloroethylene or Tetrachloroethylene with 2-Alkoxyethanols at 303.15 K and 313.15 K". Journal of Chemical & Engineering Data. 42 (2): 365–367. doi:10.1021/je960316f. ISSN 0021-9568.
^ "Safety Data Sheet". Retrieved 23 February 2022.
^ Trichloroethylene on OSHA
^ Environmental Health Criteria: Trichloroethylene International Programme on Chemical Safety
^ FischerSci Trichloroethylene SDS
^ ^a ^b "Trichloroethylene". Immediately Dangerous to Life or Health Concentrations (IDLH). National Institute for Occupational Safety and Health (NIOSH).
^ Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.
^ Trichloroethylene (TCE) on ATSDR

[:1-1] "Trichloroethylene". Sigmaaldrich.com. Retrieved 20 October 2014.

[chemsrc-2] "Trichloroethylene". www.chemsrc.com.

[PGCH-3] ^ ^a ^b ^c ^d ^e ^f NIOSH Pocket Guide to Chemical Hazards. "#0629". National Institute for Occupational Safety and Health (NIOSH).

[VenkatesuluVenkatesu1997-4] Venkatesulu, D.; Venkatesu, P.; Rao, M. V. Prabhakara (1997). "Viscosities and Densities of Trichloroethylene or Tetrachloroethylene with 2-Alkoxyethanols at 303.15 K and 313.15 K". Journal of Chemical & Engineering Data. 42 (2): 365–367. doi:10.1021/je960316f. ISSN 0021-9568.

[5] "Safety Data Sheet". Retrieved 23 February 2022.

[6] Trichloroethylene on OSHA

[7] Environmental Health Criteria: Trichloroethylene International Programme on Chemical Safety

[8] FischerSci Trichloroethylene SDS

[IDLH-9] "Trichloroethylene". Immediately Dangerous to Life or Health Concentrations (IDLH). National Institute for Occupational Safety and Health (NIOSH).

[10] Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.

[atsdr-11] Trichloroethylene (TCE) on ATSDR

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