Transfer RNA
| tRNA | |
|---|---|
Illustration of tRNA in translation | |
| Identifiers | |
| Symbol | t |
| Rfam | RF00005 |
| Other data | |
| RNA type | gene, tRNA |
| PDB structures | PDBe 3icq, 1asy, 1asz, 1il2, 2tra, 3tra, 486d, 1fir, 1yfg, 3eph, 3epj, 3epk, 3epl, 1efw, 1c0a, 2ake, 2azx, 2dr2, 1f7u, 1f7v, 3foz, 2hgp, 2j00, 2j02, 2ow8, 2v46, 2v48, 2wdg, 2wdh, 2wdk, 2wdm, 2wh1 |
Transfer ribonucleic acid (tRNA), formerly referred to as soluble ribonucleic acid (sRNA),[1] is an adaptor molecule composed of RNA, typically 76 to 90 nucleotides in length (in eukaryotes).[2] In a cell, it provides the physical link between the genetic code in messenger RNA (mRNA) and the amino acid sequence of proteins, carrying the correct sequence of amino acids to be combined by the protein-synthesizing machinery, the ribosome. Each three-nucleotide codon in mRNA is complemented by a three-nucleotide anticodon in tRNA. As such, tRNAs are a necessary component of translation, the biological synthesis of new proteins in accordance with the genetic code.
- ^ Plescia OJ, Palczuk NC, Cora-Figueroa E, Mukherjee A, Braun W (October 1965). "Production of antibodies to soluble RNA (sRNA)". Proceedings of the National Academy of Sciences of the United States of America. 54 (4): 1281–1285. Bibcode:1965PNAS...54.1281P. doi:10.1073/pnas.54.4.1281. PMC 219862. PMID 5219832.
- ^ Sharp SJ, Schaack J, Cooley L, Burke DJ, Söll D (1985). "Structure and transcription of eukaryotic tRNA genes". CRC Critical Reviews in Biochemistry. 19 (2): 107–144. doi:10.3109/10409238509082541. PMID 3905254.